Over-the-counter remedies can safely treat most cases of mild to moderate red eyes. Popular remedies include:
Naphazoline, which is found in drugs such as Clear Eyes Itchy Eye Relief. Naphazoline is a decongestant that can treat redness caused by allergic reactions and minor irritation.
Tetrahydrozoline, which is found in drops such as Visine. Tetrahydrozoline is a decongestant that, like naphazoline, clears redness caused by allergy, exhaustion, and irritation.
Eye lubricant drops. Many drops are available, most of which use lipids to mimic real tears. There is some debate among eye doctors about whether preservatives in some eye drops are safe. Preservative-free drops are available.